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Updated: Sep 17, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Published on: October 26, 2015

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细胞透干扰剂的机械设计,以实现依赖相互作用

Vanda Gunning1,2, Matthew Batchelor1,2, Krista K Alexander3

  • 1Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom.

Research square
|June 30, 2025
PubMed
概括

研究人员开发了一种新型的碳化合物合 (SP TACC3),它破坏了TACC3 / CHC相互作用,增强了线粒状的稳定性. 这种通过干扰细胞分裂,显示出癌症治疗的潜力.

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