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Updated: Sep 17, 2025

A Protocol for Computer-Based Protein Structure and Function Prediction
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A Protocol for Computer-Based Protein Structure and Function Prediction

Published on: November 3, 2011

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通过MSA工程和广泛的模型采样和排名在CASP16中提升AlphaFold蛋白质三级结构预测

Jian Liu1, Pawan Neupane1, Jianlin Cheng1

  • 1Department of Electrical Engineering & Computer Science, NextGen Precision Health, University of Missouri, Columbia, Missouri, 65211, United States of America.

Research square
|June 30, 2025
PubMed
概括

MULTICOM4通过增强多个序列对齐 (MSA) 和采用整体质量评估来改善对具有挑战性的目标的蛋白质结构预测. 该系统在CASP16中实现了最高性能,超过了标准AlphaFold3.

关键词:
阿尔法折叠是什么意思深度学习是一种深度学习.蛋白质质量评估模型 蛋白质质量评估模型蛋白质结构预测 蛋白质结构预测

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