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Updated: Sep 17, 2025

Flow Cytometry-Based Quantification and Analysis of Myocardial B-Cells
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通过PKA介导的BMAL1酸化促进了β1-腺素受体自身抗体诱导的心肌细胞死亡

Yuan Yuan1, Jiayan Feng1, Lingxia Xue1

  • 1Research Institute of Circadian Rhythm and Disease, Shanxi Medical University, Taiyuan, China.

iScience
|June 30, 2025
PubMed
概括

贝塔-1 adrenoceptor自抗体 (β1-AA) 破坏心脏细胞中BMAL1蛋白的昼夜节律,导致其积累并导致心肌细胞死亡. 这一过程涉及到BMAL1.1的特定酸化.

关键词:
心血管医学 心血管医学细胞生物学 细胞生物学

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