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Updated: Jul 2, 2026

Aip1p Dynamics Are Altered by the R256H Mutation in Actin
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通过ARTP突变和发酵优化改善fidaxomicin的生产在Actinoplanes和Deccanensis中

Jing-Yi Ruan1, Huang Xie1, Yi-Lei Zheng1

  • 1First Affiliated Hospital and Institute of Pharmaceutical Biotechnology, Zhejiang University School of Medicine, Hangzhou, China.

Synthetic and systems biotechnology
|June 30, 2025
PubMed
概括

研究人员提高了fidaxomicin的产量,用于治疗困难菌感染 (CDI). 他们在15L发酵器中实现了创纪录的3.9g/L产量,为工业抗生素制造铺平了道路.

关键词:
在ARTP的突变发生过程中.双报告员系统的系统.发酵优化优化发酵的优化菲达克索米奇因 (Fidaxomicin) 是一种药物.

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