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儿童肥胖及其与维生素D的相关性:系统性审查
America Aldana1, Welaa Aljaroudi1, Cheryl Estes1
1Biochemistry and Genetics, Saint James School of Medicine, Arnos Vale, VCT.
Cureus
|June 30, 2025
概括
维生素D缺乏与儿童肥胖有显著联系,较低的维生素D水平与较高的体重指数 (BMI) 相相关. 这一综述强调了对肥胖儿童维生素D缺乏症的查的重要性.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 儿童肥胖是一个日益严重的全球健康问题,具有显著的长期影响.
- 越来越多地认识到维生素D缺乏是导致儿童各种健康问题的潜在因素.
研究的目的:
- 系统地审查有关维生素D缺乏和儿童肥胖之间的联系的现有数据.
- 确定维生素D缺乏对儿科健康状况的意义和预测价值,特别是在肥胖儿童中.
主要方法:
- 通过使用MEDLINE,Google Scholar,PubMed和JSTOR等数据库进行了系统的文献审查.
- 使用关键词确定了相关研究:"维生素D"",儿童肥胖"",儿科"和"维生素D缺乏".
- 评估了研究质量,并提取和分析了有关维生素D缺乏和儿童肥胖之间的关系的数据.
主要成果:
- 大多数审查的研究发现,维生素D缺乏和儿童肥胖之间存在统计学上显著的关联.
- 在体质指数 (BMI) 和维生素D水平之间观察到适度的反相关性 (r ≈ -0.299,p<0.01).
- 在肥胖儿童中,缺乏维生素D的几率显著增加 (整体几率比 = 2.6,95% CI: 1.4-4.76).
结论:
- 证据强烈支持维生素D缺乏和儿童肥胖之间存在显著的关联,具有潜在的双向影响.
- 研究结果表明,需要对肥胖儿童进行维生素D缺乏症查,反之亦然,以改善患者护理,并为有针对性的干预提供信息.
- 需要进一步的研究来澄清因果机制,并优化治疗和预防两种条件的策略.
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