输血中的抗M抗体:服务延迟和支出的一个被低估的因素
Suman S Routray1, Nirupama Sahoo1, Biswajit Bhuyan2
1Department of Immunohaematology and Blood Transfusion, Kalinga Institute of Medical Sciences, Bhubaneswar, IND.
Cureus
|June 30, 2025
概括
捐赠者和患者中具有临床意义的抗M抗体显著延迟输血,并使输血前检测成本增加了十倍. 寻找M阴性血液单位需要先进的中心和合作来克服挑战.
科学领域:
- 免疫血液学 免疫血液学
- 输血医学 输血医学
背景情况:
- 抗M抗体对输血服务的影响尚未得到充分证实.
- 抗M抗体可能导致输血并发症并影响血液供应.
研究的目的:
- 在捐赠者和患者中确定临床显著的抗M抗体的流行率.
- 分析抗M对输血周转时间和成本的影响.
主要方法:
- 两年来免疫血液学和电子病历的回顾性审查.
- 在献血者和输血请求中检测抗M抗体的分析.
主要成果:
- 在7155例捐赠中1例和2380例患者中1例中发现了抗M抗体.
- 对抗M的测试成本增加了十倍,中位数的周转时间为24小时.
- 由于难以找到M阴性单位,手术手术延迟了平均两天.
结论:
- 临床显著的抗M抗体对输血服务构成挑战,导致延迟和增加成本.
- 建立M阴性捐赠者数据库和中心间合作对于管理抗M病例至关重要.
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