偏好的治疗和预期风险在冠状动脉干预患者与周围动脉疾病:心脏病学家的观点与试验数据数据对比
Tineke H Pinxterhuis1,2, Clemens von Birgelen1,2, Eline H Ploumen1,2
1Department of Cardiology, Thoraxcentrum Twente, Medisch Spectrum Twente, Enschede, The Netherlands.
CJC open
|June 30, 2025
概括
心脏病学家准确地识别了冠状动脉疾病和外周动脉疾病 (PADs) 的患者进行皮肤穿冠状动脉干预 (PCI) 的风险增加. 然而,他们高估了PAD患病率,并显示了不同的治疗偏好,突出了需要更多数据的需求.
科学领域:
- 心脏病学 心脏病学
- 血管医学 血管医学
- 干预心脏病学 干预心脏病学
背景情况:
- 冠状动脉疾病 (CAD) 和外周动脉疾病 (PAD) 在老龄化西方人口中的患病率增加.
- 同时PAD患者的皮肤冠状动脉干预 (PCI) 存在治疗挑战.
- 对心脏病学家对患有PAD的PCI患者的治疗偏好和风险感知的理解有限.
研究的目的:
- 将心脏病学家对治疗和并发症风险的看法与PCI试验中的患者级数据进行比较.
- 评估心脏病学家对PCI患者PAD患病率和相关风险的认识.
- 调查PAD如何影响心脏病专家之间的治疗决策.
主要方法:
- 这是一项涉及心脏病专家的基于调查的研究.
- 调查答案与BIO-RESORT和BIONYX PCI试验中的患者数据的比较.
- 在PCI患者中估计与实际PAD患病率的分析.
- 评估PAD的PCI患者估计与观察到的并发症率.
主要成果:
- 心脏病学家正确地确定了PAD日益增长的患病率,但高估了PCI患者当前的患病率 (估计为22%,实际为7.3%).
- 心脏病学家准确地预测了PAD的PCI患者的出血,心肌梗塞和心脏死亡的3年风险增加.
- 同时的PAD显著影响了心脏病学家的首选治疗策略,选择的差异很大.
结论:
- 心脏病学家对患有PAD的PCI患者不良事件的风险感知在很大程度上是准确的.
- 首选冠状动脉治疗的差异凸显了对这一患者群体需要更多基于证据的指导方针的需要.
- 需要增加临床关注和进一步的研究,以优化对患有PAD的PCI患者的护理.
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