个性化功能和结构语言侧面性在叶和它们对记忆的影响
Ankeeta Ankeeta1, Qirui Zhang1, Sam Sharifzadeh Javidi1
1Department of Neurology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Human brain mapping
|June 30, 2025
概括
研究了大脑语言侧面性及其与大脑结构和记忆的联系. 个性化测量显示了功能和结构不对称性之间的强烈相关性,影响患者和健康个体的记忆组织.
科学领域:
- 神经科学是一个神经科学.
- 认知神经科学 认知神经科学
- 神经成像是一种神经成像.
背景情况:
- 了解功能性大脑不对称性,特别是语言侧面化,以及它们与结构不对称性的联系是有限的.
- 功能语言不对称性对记忆组织的影响需要进一步研究.
研究的目的:
- 评估半球语言横向性和灰色物质结构不对称性之间的一致性.
- 确定功能语言不对称性是否影响记忆的半球组织.
主要方法:
- 从261名参与者 (单侧叶患者和健康对照组) 获得结构和功能MRI数据.
- 针对功能和结构数据计算的标准和目标语言侧面性指数 (LI).
- 雇佣了歧视性和部分最小平方分析来评估群体差异和认知关系.
主要成果:
- 与健康参与者相比,在左叶患者 (LTLE) 中发现了语言横向性的显著变化.
- 功能性LI和结构性LI (ST-LI) 之间存在强烈的相关性.
- 有针对性的LIs和ST-LIs有效地将TLE患者与对照患者区分开来,ST-LIs是最强的预测因子.
- 语言和视觉记忆显示直接依赖于向的LI,特别是在健康参与者和LTLE患者中.
结论:
- 个性化,特定于区域的措施对于理解语言横向性及其结构基础至关重要.
- 功能性语言不对称性显著影响记忆组织,在患者群体和健康个体之间产生不同的影响.
- 这些发现突出了大脑结构,语言功能和记忆等认知过程之间的复杂关系.
关键词:
语言横向化 (lateralization) 是一种语言横向化.语言重组语言重组记忆中的侧面化 (lateralization).结构不对称的结构不对称.在叶发作.语言记忆 语言记忆视觉记忆 视觉记忆 视觉记忆更多相关视频
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