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Updated: Sep 17, 2025

A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3
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通过对JAK2 mRNA的转录后调节,ERH调节II型干扰素免疫信号传递

Adrian Soderholm1,2,3, Milica Vunjak1,2,3, Melanie de Almeida3,4

  • 1Max Perutz Labs, Vienna BioCenter Campus (VBC), Dr. -Bohrgasse 9, 1030, Vienna, Austria.

Nucleic acids research
|June 30, 2025
PubMed
概括

II型干扰素 (IFNγ) 信号传递对于免疫和癌症治疗至关重要. 研究人员确定了ERH和调节JAK2mRNA成熟的相关因素,揭示了IFNγ反应的新控制点.

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