卡普兰综合征的四年随访:一个病例报告
Ling Wang1, Yanling Liu2, Yibin Zhang3
1Department of Endocrinology and Rheumatology, the Third People's Hospital of YuHang District, China.
The Journal of international medical research
|June 30, 2025
概括
卡普兰综合征是一种罕见的肺部疾病,涉及煤炭工人的类风湿性关节炎和肺结节. 本案例研究强调了通过药物组合的成功诊断和管理,导致稳定的患者结果.
科学领域:
- 类风湿病学 类风湿病学
- 肺部病理学 肺部病理学
- 职业医学 职业医学是专业的.
背景情况:
- 卡普兰综合征或类风湿性肺炎症,在患有肺炎症的患者中呈现肺结节和类风湿性关节炎.
- 由于发病率低且在肺部CT扫描上具有多个结节的特征,它很少被诊断出来,往往导致误诊.
- 早期识别和管理对于改善患者预后至关重要.
研究的目的:
- 报告一名60岁男性病人的卡普兰综合征病例.
- 详细说明诊断过程,包括临床表现,实验室发现和成像.
- 为了说明卡普兰综合征特定治疗方案的有效性.
主要方法:
- 一名60岁的男性患者出现了关节和多关节痛.
- 诊断工作包括实验室测试 (风湿性因素,抗素抗体,ESR) 和胸部高分辨率计算机断层扫描 (HRCT).
- 多学科咨询和职业史是诊断的组成部分.
主要成果:
- 实验室结果显示,风湿因子升高,抗素抗体和ESR.
- 胸部HRCT显示了多个双边肺结节.
- 患者接受了甲基prednisolone,甲甲和氧化的维护疗法.
结论:
- 卡普兰综合征的确诊基于临床,实验室,成像和职业发现.
- 在4年的随访期间,治疗方案导致稳定的关节痛和肺结节.
- 这一案例强调了在有相关职业病史和类风湿症状的患者中考虑卡普兰综合征的重要性.
相关概念视频
Case Studies
11.3K
There are many research methods available to psychologists in their efforts to understand, describe, and explain behavior and the cognitive and biological processes that underlie it.
11.3K
Longitudinal Research
11.7K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
11.7K
Classification of Illness
9.4K
The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
9.4K
Cushing Syndrome I: Introduction
36
Cushing syndrome refers to the collection of clinical manifestations that arise when tissues are exposed to excessive amounts of cortisol or cortisol-like medications over an extended period. Cortisol, a glucocorticoid produced by the adrenal cortex, regulates metabolism, immune responses, and the body’s adaptation to stress. When its concentration remains chronically elevated, these physiological pathways become dysregulated, resulting in the characteristic features of the...
36
Cushing Syndrome II: Pathophysiology
24
Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features...
24
Cirrhosis I: Introduction
28
Cirrhosis is a chronic, irreversible liver disease characterized by the widespread replacement of healthy liver tissue with fibrotic scar tissue and the formation of regenerative nodules.Etiology of cirrhosisCirrhosis results from sustained liver injury that triggers progressive fibrosis and structural remodeling. The underlying causes are diverse, encompassing common and less frequent clinical conditions. Regardless of the origin, all causes lead to chronic inflammation, hepatocyte loss, and...
28


