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数字皮肤显微镜对获得的纵向黑色素斑的后续检查
Elvira Moscarella1, Gabriella Brancaccio1, Zoe Apalla2
1Dermatology Unit, University of Campania L.Vanvitelli, Naples, Italy.
概括
数字皮肤显微镜通过监测纵向黑色素瘤来帮助诊断早期的指甲单元黑色素瘤. 在随访期间,新的颜色或增加的色素要求进行活检,以排除恶性瘤.
科学领域:
- 皮肤病学 皮肤病学
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 早期诊断指甲单元黑色素瘤是一项挑战.
- 纵向性黑色素需要对恶性瘤进行仔细监测.
- 皮肤镜监测对于区分良性和恶性色素指甲病变至关重要.
研究的目的:
- 为了表征纵向黑色心肌病的临床和皮肤学变化.
- 评估顺序数字监控在管理指甲单位色素损伤方面的有用性.
- 为了识别皮肤上可见的特征,在纵向黑色肌的恶性病.
主要方法:
- 对单个获得的有色素指甲带的成年患者进行了回顾性横截面研究.
- 随着时间的推移,对临床和皮肤镜特征进行了连续的数字监测.
- 切除病变的组织学诊断;未切除病例的最低1年稳定性.
主要成果:
- 在中位数17个月的随访后,在62个病变中发现了6种in-situ黑色素瘤 (9.7%).
- 与良性病变相比,恶性指甲带的颗粒性色素增加 (33.3%与3.6%相比),新颜色增加 (50%与8.9%相比),色素强度增加 (83.3%与14.3%相比).
- 在随访期间,新的颜色,颗粒色素或增加的色素强度是恶性瘤的重要指标.
结论:
- 数字皮肤镜后续检查对于管理不确定的纵向黑色心病病例是有价值的.
- 新颜色的出现,颗粒色素或增加的色素强度需要活检.
- 这种监测策略有助于早期发现指甲单元黑色素瘤.
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