在性接触者中感染克拉米迪亚和淋病的阳性,STI监测网络,2021-2023年
Eloisa Llata1, Brandi Danforth2, Jennifer Tang3
1Centers for Disease Control and Prevention, Surveillance and Data Management Branch, Division of STD Prevention (NCCHSTP).
Sexually transmitted diseases
|June 30, 2025
概括
克拉米迪亚 (CT) 和淋病 (NG) 的性接触者具有很高的感染率,并观察到显著的阳性. 临床检测可以优化这些性传播感染的抗生素使用.
科学领域:
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
- 流行病学 流行病学
背景情况:
- 曾与被诊断患有克拉米迪亚 (CT) 或淋病 (NG) 的伴侣发生过性接触的个人面临感染这些性传播感染 (STIs) 的风险较高.
- 目前的指导方针建议在性接触时使用抗微生物药物治疗,但仍存在对不必要使用抗生素的可能性的担忧.
研究的目的:
- 评估感染个体的性接触者中克拉米迪亚 (CT) 和淋病 (NG) 的阳性率.
- 评估点照顾测试对优化这一群体中抗菌素使用的实用性.
主要方法:
- 从2021年1月到2023年10月在10家性传播疾病诊所进行的患者访问的回顾性审查.
- 分析CT和NG阳性率,按患者群体 (女性,与男性发生性关系的男性[MSM],仅与女性发生性关系的男性[MSW]) 和症状状况分层.
主要成果:
- 总体而言,11,072人 (6.8%) 的接触者被确定为CT和/或NG. 在CT接触者中,CT阳性为35%,在NG接触者中,NG阳性为31%.
- 根据患者群体的症状状况,CT阳性并没有变化.
- 在有症状的与无症状的MSM和MSW中,NG阳性性更高,但在女性中没有.
结论:
- 经过CT或NG的大量性接触者被发现被感染,这凸显了有效查的必要性.
- 在MSW接触者中,CT感染最为普遍,而NG感染在女性接触者中最为普遍.
- 观察到的阳性率和显著的负面测试百分比 (~60%) 表明,临床检测可以提高抗菌药物管理和患者护理.
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