Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Variability: Analysis01:11

Variability: Analysis

192
Measures of variability are statistical metrics that reveal the dispersion pattern within a dataset. They are pivotal in biostatistics, providing insights into the heterogeneity within health and biological data. Variability signifies the degree to which data points diverge from one another, helping researchers understand the potential range of values and associated uncertainty within the data.
The range is a simple measure of variability, indicating the difference between the highest and...
192

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Epidemiology of Pertussis and the Screening Value of WBC and Lymphocyte Percentage.

International journal of general medicine·2024
Same author

An exploration of the value of NLR, PLR, LMR, and WBC × CRP for the diagnosis and treatment of influenza B in adults.

Medicine·2024
Same author

Effects of different pepsinogen cut offs in the screening of apparently healthy people.

Clinical chemistry and laboratory medicine·2022
Same author

Transition to seizure: ictal discharge is preceded by exhausted presynaptic GABA release in the hippocampal CA3 region.

The Journal of neuroscience : the official journal of the Society for Neuroscience·2012
Same author

AccERK2, a map kinase gene from Apis cerana cerana, plays roles in stress responses, developmental processes, and the nervous system.

Archives of insect biochemistry and physiology·2012
Same author

[Research on the issues in the process of post-market surveillance for medical devices based on the typical case analysis].

Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation·2012

相关实验视频

Updated: Sep 17, 2025

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes
05:58

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes

Published on: March 22, 2022

4.2K

不同的SCC-Ag参考间隔的临床应用值.

Qi Xie1, Longying Zhu1,2, Liang Zhang1

  • 1Department of Clinical Laboratory, First People's Hospital of Linping District, Hangzhou, Hangzhou, Zhejiang Province, People's Republic of China.

Medicine
|June 30, 2025
PubMed
概括

这项研究为状细胞癌抗原 (SCC-Ag) 设定了≤2.2μg/L的新参考间隔. 与现有的标准相比,这种局部定制的间隔可以提高SCC-Ag测试的诊断准确度和临床决策.

关键词:
这就是SCC-Ag.诊断值是指诊断值的使用情况.健康检查健康检查积极的利率是积极的利率.参考时间间隔是参考时间间隔.

更多相关视频

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
07:24

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

1.8K
Using Reference Reagents to Confirm Robustness of Cytokine Release Assays for the Prediction of Monoclonal Antibody Safety
06:37

Using Reference Reagents to Confirm Robustness of Cytokine Release Assays for the Prediction of Monoclonal Antibody Safety

Published on: September 15, 2023

738

相关实验视频

Last Updated: Sep 17, 2025

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes
05:58

Evaluation of a Point-of-Care Testing Analyzer for Measuring Peripheral Blood Leukocytes

Published on: March 22, 2022

4.2K
A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy
07:24

A Precision Medicine Tool for Measurement and Monitoring of Hemoglobin S in Sickle Cell Disease Patients Receiving Transfusion Therapy

1.8K
Using Reference Reagents to Confirm Robustness of Cytokine Release Assays for the Prediction of Monoclonal Antibody Safety
06:37

Using Reference Reagents to Confirm Robustness of Cytokine Release Assays for the Prediction of Monoclonal Antibody Safety

Published on: September 15, 2023

738

科学领域:

  • 临床化学 临床化学
  • 瘤标记物 瘤标记物
  • 生物统计学 生物统计学

背景情况:

  • 状细胞癌抗原 (SCC-Ag) 是一种具有既定参考间隔的瘤标记物.
  • 现有的SCC-Ag参考间隔可能不适合所有种群.
  • 准确的参考间隔对于有效的癌症查和诊断至关重要.

研究的目的:

  • 为SCC-Ag.建立一个群体特定的参考区间.
  • 与现有的SCC-Ag参考区间对比,评估拟议的SCC-Ag参考区间的临床实用性.
  • 提高SCC-Ag测试对临床决策的准确性.

主要方法:

  • 对5251名健康个体进行了回顾性分析,以确定局部SCC-Ag参考区间 (≤2.2μg/L).
  • 在6191名健康受试者中评估查疗效,使用建议和制造商间隔.
  • 在948名患者的诊断性能评估中,比较了两个SCC-Ag参考间隔.

主要成果:

  • 建议的SCC-Ag参考间隔 (≤2.2μg/L) 在健康人群中产生较低的阳性率 (1.696%) 与制造商间隔 (7.931%) 相比.
  • 新的间隔显示出更高的特异性,积极的预测值,尤登指数和整体准确性.
  • 灵敏度和负预测值在拟议的时间间隔下较低.

结论:

  • 拟议的SCC-Ag参考间隔≤2.2μg/L高于制造商提供的在受研究人群中进行查和诊断的间隔.
  • 这种本地建立的参考间隔提供了更好的临床实用性和决策支持.
  • 在不同种群中可能需要进一步验证.