禅克口腔内镜肌切除术对喉囊的管理是安全有效的:一个多中心回顾性队列研究
Benjamin Norton1,2,3, Katie Siggens4, Apostolis Papaefthymiou1
1Digestive Diseases and Surgical Institute, Cleveland Clinic London, London, UK.
Digestive diseases (Basel, Switzerland)
|June 30, 2025
概括
禅克口腔内镜肌切除术 (Z-POEM) 是一种安全有效的微创治疗方法,用于治疗禅克口腔分离器 (ZD). 这种内镜方法取得了很高的成功率,证明了它对这种疾病患者的价值.
科学领域:
- 胃肠病学 胃肠病学
- 内視鏡外科手術 內視鏡外科手術
- 消化系统疾病 消化系统疾病
背景情况:
- 克分歧管 (ZD) 是一个喉-食道结口的外囊,导致食不适和反.
- 对于ZD的传统手术涉及侵入性,并发症和复发.
- 禅克口腔内镜肌切除术 (Z-POEM) 是一种微创内镜替代方案.
研究的目的:
- 评估Z-POEM在英国的安全性和有效性.
- 评估Z-POEM用于Zenker分泌体治疗的技术和临床成功率.
主要方法:
- 在四个英国中心 (2019-2024) 连续接受Z-POEM的患者的回顾性分析.
- 收集的数据包括人口统计,技术/临床成功和不良事件.
- 临床成功定义为失消症得分减少到≤1而不需要重新干预.
主要成果:
- 在61名患者中100%的技术成功;在11.2个月的平均随访期间,93.1%的临床成功.
- 平均囊袋大小为37.3毫米;复发率为11.1%.
- 8.5% (AGREE II级) 的不良事件;用于纤维化的混合程序.
结论:
- Z-POEM是一种安全有效的内镜治疗Zenker分离器.
- 高技术和临床成功率支持Z-POEM的采用.
- 混合手术对于下纤维化病例来说是一个可行的选择.
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