相关实验视频

Updated: Sep 17, 2025

Dissecting Cell-Autonomous Function of Fragile X Mental Retardation Protein in an Auditory Circuit by In Ovo Electroporation
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Published on: July 6, 2022

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FMR1 KH0-KH1域坐标m6在脆弱X综合征中的A结合和相分离

Xian Zhou1, Chen-Jun Guo2, Rui Wang2

  • 1State Key Laboratory of Cardiology and Medical Innovation Center, Department of Reproductive Medicine Center, Shanghai East Hospital, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China; School of Life Science and Technology, ShanghaiTech University, Shanghai, China.

Experimental cell research
|June 30, 2025
PubMed
概括

脆弱的X信使核糖蛋白1 (FMR1) 域KH1结合m6ARNA,而KH0调节液-液相分离 (LLPS). KH0中的突变破坏了RNA结合,并导致异常的LLPS,将m6A与脆弱X综合征联系起来.

关键词:
FMR1 FMR1 的使用情况.脆弱的X综合征是什么?KH0 域名 域名阶段分离 阶段分离 阶段分离m(6) 一个RNARNA.

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