全外体测序揭示了神经内分泌新生体中生殖线变化的高患病率

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Vineeth Sukrithan1, Isaiah Boateng1, Sandya Liyanarachchi1

  • 11The Ohio State University, Columbus, OH.

Journal of the National Comprehensive Cancer Network : JNCCN
|June 30, 2025
PubMed
概括

近一半的神经内分泌瘤 (NEN) 患者有生殖系变异. 生殖线MUTYH (gMUTYH) 变化与高瘤突变负担和免疫透相关,表明对免疫检查点抑制 (ICI) 的潜在反应.

关键词:
马蒂斯 (MUTYH) 是一个有趣的小说.细菌线的生殖线生殖系变体的生殖系变体神经内分泌新生体的神经内分泌新生体基于整个外体的生殖系概况,以整个外体为基础.

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