前载视觉场测试的纵向变化结果
Jeremy C K Tan1,2, Jonathan Crowston2,3, Katharina Bell3,4
1Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia.
The British journal of ophthalmology
|June 30, 2025
概括
在一次访问期间,每只眼睛进行两次视野 (VF) 测试,称为前载,可显著减少青光眼患者的纵向变异性. 这种方法提高了周边数据的可靠性,以便更好地监测疾病.
科学领域:
- 眼科医生 眼科 眼科
- 青光眼的诊断 青光眼的诊断
- 视觉现场测试 视觉现场测试
背景情况:
- 准确的视野 (VF) 测试对于青光眼的诊断和管理至关重要.
- 在VF数据的纵向变异性可能会使疾病进展的评估复杂化.
- 当前的测试协议可能无法始终捕获可靠的周边数据.
研究的目的:
- 评估是否在同一次检查中进行两次VF测试,增加周边数据并减少纵向变化.
- 为了比较前部装载的方法与传统的单测试每眼的方法.
主要方法:
- 一项前性纵向研究,涉及333名受试者 (498只眼睛) 患有健康,可疑或眼疾病.
- 两个SITA-Faster VF测试 (T1和T2) 进行了每次眼睛每次访问,连续五次访问.
- 线性混合效应模型将前载方法 (T1和T2的平均值) 与非前载方法 (仅T1) 进行了全球和点对点灵敏度的比较.
主要成果:
- 前载方法显示总灵敏度的残余标准偏差 (1.19对1.36dB) 和平均绝对残余 (0.69对0.78dB) 显著较小,表明变化性降低.
- 在前载方法中,点向灵敏度变化更为负面 (-0.18比-0.14dB/年),平均绝对残留值显著较小 (1.24比1.53dB).
- 即使排除了不可靠的测试 (错误阳性>15%) 后,也观察到前装量的变化减少.
结论:
- 在同一次访问中进行前置视觉现场测试可以降低全球和定点灵敏度的纵向变化.
- 这种方法可能有助于临床医生满足对玻璃眼瘤监测的最低测试频率建议.
- 前端加载提供了一种更可靠的方法,通过视觉现场测试来跟踪青光眼的进展.
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