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Updated: Jun 17, 2026

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues
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爱斯坦-巴尔病毒和多发性硬化症:我们从中吸取了教训,以开发更好的非人类灵长类动物模型.

Hai Duc Nguyen1, Daesik Kim2, Yong-Hee Kim2

  • 1Division of Microbiology, Tulane National Primate Research Center, Tulane University, Covington, LA, USA.

Experimental & molecular medicine
|June 30, 2025
PubMed
概括

爱斯坦-巴尔病毒 (EBV) 与多发性硬化症 (MS) 有关. 本综述探讨了EBV风险因素,并提出了非人类灵长类动物 (NHP) 模型来研究多发性硬化症的发病过程和开发治疗方法.

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EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...