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Updated: Sep 17, 2025

A Reporter Based Cellular Assay for Monitoring Splicing Efficiency
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Published on: September 15, 2021

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在成熟的B细胞瘤中,疾病特异性的U1结合体RNA突变

Ferran Nadeu1,2, Shimin Shuai3, Guillem Clot4,5,6

  • 1Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. nadeu@recerca.clinic.cat.

Leukemia
|June 30, 2025
PubMed
概括

复发的U1结合体RNA突变导致慢性淋巴细胞白血病 (CLL) 和其他B细胞癌症的进展. 这些发现将U1确定为B细胞恶性瘤中的关键驱动基因.

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