UQCRC1是阿尔茨海默病认知障碍的关键致病决定因素和潜在治疗标

Jing Zhang1,2, Zuoxi Wu1, Zonghong Long1

  • 1Department of Anesthesiology, The Xinqiao Hospital, Army Medical University, Chongqing, China.

PubMed
概括

降低的乌比基诺-细胞染色体c还原酶核心蛋白1 (UQCRC1) 通过损害 lysosomal 功能,使阿尔茨海默病 (AD) 症状恶化. 通过AMPK信号恢复UQCRC1,为AD提供了一个潜在的治疗策略.

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