运动治疗和多病症患者的自我管理支持:一个随机和受控试验
Søren T Skou1,2, Mette Nyberg3, Mette Dideriksen3,4
1The Research and Implementation Unit PROgrez, Department of Physiotherapy and Occupational Therapy, Næstved-Slagelse-Ringsted Hospitals, Slagelse, Denmark. stskou@health.sdu.dk.
Nature medicine
|June 30, 2025
概括
运动疗法和自我管理支持显著改善了12个月多重疾病的成年人与健康相关的生活质量 (HRQoL). 这种联合干预措施证明优于单独的常规护理,提高了患者的幸福感,而不会影响安全.
科学领域:
- 老年学是一门学科.
- 临床医学 临床医学
- 康复科学 康复科学 康复科学
背景情况:
- 多病症是一个越来越大的挑战,对有效的管理策略的证据有限.
- 运动治疗和自我管理支持被认为是慢性疾病的有希望的干预措施.
研究的目的:
- 为了评估个性化运动治疗和自我管理支持计划的有效性,与单独的常规护理相比,在多病症的成年人中改善与健康有关的生活质量 (HRQoL).
主要方法:
- 一个务实的,多中心的,评估者盲目的随机对照试验 (MOBILIZE) 涉及228名患有两种或更多长期疾病的成年患者.
- 参与者被随机分配到12周的干预 (运动治疗和自我管理支持) 加上通常的护理,或仅仅是通常的护理.
- 主要结果是HRQoL,使用12个月后的EQ-5D-5L进行评估,次要结果包括功能表现,体力活动和患者报告的结果.
主要成果:
- 干预组与通常护理组相比,HRQoL在统计学上显著改善 (调整后的平均差异:0.064分;95%CI:0.014-0.115).
- 干预组的自我评估健康状况也显著改善 (调整后的平均差异:6.9分;95% CI:1.8-12.1).
- 两组之间没有观察到严重不良事件的显著差异,这表明安全性概况相似.
结论:
- 个性化运动治疗与自我管理支持相结合,是改善12个月多病症成人HRQoL的有效策略.
- 该干预表明了有利的安全概况,与通常的护理相美.
- 需要进一步的研究来澄清这些发现的临床相关性.
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