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循环中的乌伯利诺基因增加了严重的酒精诱导性肝炎的炎症和皮质类固醇不响应

Manisha Yadav1, Abhishak Gupta2, Babu Mathew1

  • 1Department of Molecular and Cellular Medicine, Institute of Liver and Biliary Sciences, New Delhi 110070, India.

Molecular therapy : the journal of the American Society of Gene Therapy
|July 1, 2025
PubMed
概括

在严重的酒精相关性肝炎 (SAH) 中,高的乌比利诺基因水平预测治疗反应不佳和早期死亡率. 肠道微生物组调节,特别是减少胆红素还原酶,可能会改善SAH患者的结果.

关键词:
bilirubin 减少酶 的作用.肠道透性的肠道透性这是一种炎症炎症炎症炎症.超级蛋白质组 (metaproteome) 是一个超级蛋白质组.没有回应的非响应者.血代谢组的血代谢普雷迪尼索隆的治疗方法响应者 响应者 响应者严重的酒精相关性肝炎已经成为了 urobilinogen.

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