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在患有糖尿病病的患者中评估左心室功能,使用二维斑点跟踪回声心脏图

Xiunan Zhang¹, Cuiping Jiang², Zhibin Ye¹

¹Department of Nephrology, Huadong Hospital, Fudan University, Shanghai, China.

Frontiers in endocrinology

|July 1, 2025

概括

糖尿病病患者表现出增加的亚临床缩功能障碍,与高胆固醇有关. 二维斑点跟踪回声心电图 (2D-STI) 有助于评估这种心脏风险.

科学领域:

心脏病学心脏病学
腎臟病學 (nephrology) 是一種醫學專業.
糖尿病学糖尿病学

背景情况:

糖尿病病 (DN) 是糖尿病 (DM) 的并发症,影响脏.
在DN患者中早期发现心脏功能障碍对于及时干预至关重要.
亚临床心脏功能障碍可能会在明显心力衰竭之前出现.

研究的目的:

为了评估DN患者的心脏功能,使用二维斑点跟踪心电回声学 (2D-STI).
为了研究白蛋白尿和早期心脏缩/透缩功能障碍之间的关联.
在DN中确定心脏功能障碍的临床风险因素.

主要方法:

招募了75名DN患者,100名DM患者和37名健康对照.
收集了临床数据,并进行了常规心声学和2D-STI.
使用2D-STI.评估全球纵向应变 (GLS) 值.

主要成果:

糖尿病患者表现出较高的亚临床左心室缩功能障碍 (GLS <18%) 比对照组.
与DM患者相比,DN患者的功能障碍患病率更高 (p<0.001).
在DN患者中,较高的胆固醇水平与亚临床缩功能障碍的风险增加有关.

结论:

在DN患者中,较高的胆固醇水平与临床下左心室缩功能障碍的增加相关.
2D-STI和GLS对于评估糖尿病患者的心脏功能非常有价值.
在DN中早期发现和治疗心脏功能障碍至关重要.

关键词:

全球纵向菌株 (GLS) 是指全球纵向菌株.专辑蛋白尿症是什么意思糖尿病性脏病糖尿病脏病亚临床左心室缩性功能障碍左心室缩性功能障碍两个维的斑点跟踪回声心脏图谱.

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