系统性血压放大:系统性审查和个人参与者的元分析
Dean S Picone1,2, Tan V Bui1, Martin G Schultz1
1Menzies Institute for Medical Research, College of Health and Medicine, University of Tasmania, Hobart, Australia (D.S.P., T.V.B., M.G.S., P.O., J.A.B., H.A., N.B.D., P.R.-T., S.P., S.W.E., J.E.S.).
Hypertension (Dallas, Tex. : 1979)
|July 1, 2025
概括
系统性血压放大在主动脉和臂动脉之间有很大差异,影响了高血压分类的准确性. 了解这种变化是改善血压测量技术的关键.
科学领域:
- 心血管生理学心血管生理学
- 高血压研究 高血压研究
- 生物医学工程 生物医学工程
背景情况:
- 静脉血压 (SBP) 放大,大动脉和臂动脉压力之间的差异,影响袖口血压 (BP) 测量的准确性.
- 有限的数据存在于侵入性测量的大动脉到腕SBP放大水平.
- 这种现象与标准BP监测中的不准确性有关.
研究的目的:
- 为了研究大动脉到腕SBP放大的侵入性测量水平.
- 探索SBP放大对高血压分类的影响.
- 为了确定对袖口BP测量准确性的潜在改进.
主要方法:
- 系统性审查和对侵袭性手臂和大动脉BP的个人参与者数据的元分析.
- 包括1151名参与者 (62±12岁,72%是男性).
- 计算SBP放大率 (臂部SBP减去大动脉SBP) 和对比大动脉和臂部BP测量之间的高血压分类.
主要成果:
- 观察到SBP放大范围广泛 (平均±SD:男性8±9毫米升,女性7±10毫米升),随着年龄的增长而下降.
- 在17.4%的参与者中,高SBP放大 (>15 mm Hg),低SBP放大 (<5 mm Hg) 在37.3%的参与者中.
- 在高血压分类中,在手臂和大动脉BP之间的中度一致 (κ=0.67) (87.4%的总体一致).
结论:
- 在男性和女性中存在大动脉到腕SBP放大显著的变异性.
- 高血压分类的实质性差异在使用手臂与大动脉BP时出现.
- 这项研究为开发更准确的袖口BP测量技术提供了洞察力.
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