为精神疾病患者戒烟和减少吸烟提供电子烟 (ESCAPE):随机对照试验的协议
Dimitra Kale1, Emma Beard1, Yan Ding2
1Department of Behavioural Science and Health, University College London, London, UK.
Addiction (Abingdon, England)
|July 1, 2025
概括
这项研究测试了电子烟是否可以帮助精神疾病患者戒烟. 这是英国首次对此群体评估电子烟的有效性和成本效益的试验.
科学领域:
- 公共卫生 公共卫生
- 临床试验 临床试验
- 心理健康研究 心理健康研究
背景情况:
- 在英国,吸烟率有所下降,但在患有精神疾病的人群中仍然很高.
- 这种持续的不平等问题是一个重大的公共卫生问题.
- 目前的戒烟支持还没有充分解决这个弱势群体的问题.
研究的目的:
- 评估提供电子烟 (e-cigarette) 起步套件用于戒烟和减少危害的有效性.
- 评估电子烟干预精神疾病成年人的成本效益.
- 在这个群体中,为戒烟的政策和实践提供信息.
主要方法:
- 一个双臂并行随机控制的优越性试验.
- 参与者:成年吸烟者被诊断患有精神疾病,在社区接受治疗.
- 干预措施:电子烟启动包加上常规护理与单独的常规护理.
主要成果:
- 主要结局:七天的流行点,六个月后一氧化碳验证的戒断.
- 二次结果:持续的禁欲,减少吸烟,心理健康症状,情绪,身体症状,成本效益,坚持和满意度.
- 在入学后一个月和六个月收集数据.
结论:
- 这是英国首次对精神疾病患者戒烟的电子烟进行大规模研究.
- 结果将为这种干预措施的有效性和经济可行性提供关键证据.
- 结果将指导未来的公共卫生战略和临床实践.
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