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变形椎体融合后子沉降的危险因素:系统性审查和元分析

Fangshan Bi¹, Wenxue Chen¹, Jie Yu²

¹Department of Spine and Joint, Beijing Fengsheng Special Hospital of Traditional Medical Traumatology and Orthopedics.

Clinical spine surgery

|July 1, 2025

概括

老年和骨端板损伤是转骨腰间合 (TLIF) 后子沉降 (CS) 的关键风险因素. 了解这些因素有助于临床决策和TLIF患者的风险评估.

科学领域:

脊柱手术的结果脊柱手术的结果
整形外科的研究研究.
生物机械工程生物机械工程

背景情况:

子沉降 (CS) 是一个常见的并发症,后转腰间体融合 (TLIF).
识别CS的风险因素对于改善外科手术结果至关重要.
之前的研究已经探索了CS的各种潜在贡献者.

研究的目的:

系统地审查和分析与子沉降 (CS) 相关的风险因素,以后转腰椎体融合 (TLIF).
为TLIF程序中的临床决策提供基于证据的见解.

主要方法:

系统审查和对2024年3月31日之前发表的研究进行元分析.
搜索的数据库包括PubMed,Scopus,Embase和谷歌学者.
计算聚合赔率比率 (OR) 和标准化平均差异 (SMD) 以95%的置信区间 (CI);评估异质性和出版偏差.

主要成果:

分析了9项涉及1403名接受TLIF治疗的患者的研究.
年龄较大 (SMD=0.27;95% CI:0.12-0.41) 和骨端板损伤 (OR=7.52;95% CI:2.08-27.17) 被确定为CS的重要风险因素.
对于子高度,BMI,骨矿物质密度,吸烟,糖尿病,性别,心肺复苏,圆盘高度或手术地点没有发现显著的关联.

结论:

高龄和骨末板损伤是TLIF后子沉降的重要风险因素.
这些发现可以为TLIF手术的临床实践和患者风险分层提供信息.
进一步的研究可能会探索针对已识别的风险因素的预防策略.

关键词:

一个TLIF就是一个TLIF.子沉降的情况这是一个元分析.有关风险因素的风险因素.系统性审查系统性审查变形形腰椎体内融合

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