麻疹和固体器官移植:诊断,治疗和预防
Stephanie M Pouch1, Akshatha Ravindra2, Sara W Dong3
1Emory University School of Medicine, Atlanta, Georgia, USA.
概括
麻疹疫情对实体器官移植 (SOT) 接受者构成风险,他们可能会出现异常表现和严重并发症. 本综述涵盖SOT患者的麻疹,重点关注预防和管理策略.
科学领域:
- 免疫学 免疫学 免疫学
- 传染性疾病 传染性疾病
- 移植医学 移植医学
背景情况:
- 全球麻疹复苏带来了重大的公共卫生挑战.
- 免疫功能低下的个体,特别是实体器官移植 (SOT) 接受者,面临严重麻疹并发症的高风险.
- 在SOT接受者的非典型表现可能会延迟诊断和治疗.
研究的目的:
- 审查SOT接受者的麻疹现有数据.
- 概述在这个脆弱人群中预防麻疹和控制感染的策略.
- 讨论麻疹传播的管理,包括来自捐赠者的病毒.
主要方法:
- 对当代数据进行全面的文献综述.
- 综合有关麻疹流行病学,临床方面和管理的信息.
- 分析预防策略和感染控制措施.
主要成果:
- 接受SOT的人面临麻疹的风险增加,因为他们的免疫力受损.
- 早期诊断和及时干预对于管理SOT患者的麻疹至关重要.
- 预防和严格的感染控制对于减轻麻疹风险至关重要.
结论:
- 预防措施,包括疫苗接种和暴露后预防,对于SOT接受者至关重要.
- 需要仔细考虑来自捐赠者的麻疹和疫苗病毒.
- 需要多方面的策略来保护SOT接收者在麻疹爆发期间.
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