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Updated: Sep 17, 2025

Chemical Inactivation of the E3 Ubiquitin Ligase Cereblon by Pomalidomide-based Homo-PROTACs
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用双特异抗体治疗多发性骨髓瘤患者的托西利祖马布预防

Andrew Kowalski1, Jillian Lykon1, Benjamin T Diamond1

  • 1Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida, United States.

Blood advances
|July 1, 2025
PubMed
概括

在治疗多发性骨髓瘤的双特异抗体治疗之前给予预防性托西利祖马布,显著减少了细胞因子释放综合征 (CRS),而不会影响治疗疗效. 这种预防性方法对在现实环境中管理副作用具有前景.

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