在经过训练的受试者中,半程马拉松跑步后骨相关和炎症生物标志物的变化
C Vassalle1, L Sabatino2, M Gaggini2
1Fondazione G. Monasterio CNR-Regione Toscana, Via G. Moruzzi 1, 56124, Pisa, Italy. cristina.vassalle@ftgm.it.
European journal of applied physiology
|July 1, 2025
概括
半程马拉松跑步增加了骨循环生物标志物,包括骨质素 (OC) 和碳氧终端原交叉链 (CTx). 这些变化在24小时内正常化,这表明它对跑步者的骨代谢有暂时的影响.
科学领域:
- 运动生理学 运动生理学
- 骨的新陈代谢 骨的新陈代谢
- 内分泌学 在内分泌学.
背景情况:
- 马拉松跑步会影响骨代谢,但人们对半马拉松,一种流行的娱乐活动知之甚少.
- 了解半程马拉松运动员的骨周转是非常重要的,因为这项赛事越来越受欢迎.
研究的目的:
- 评估半马拉松跑者与对照者的骨循环生物标志物和维生素D水平.
- 研究骨生物标志物,免疫炎症指数 (SII) 和心脏代谢参数之间的相关性.
主要方法:
- 在跑步者和对照者中测量了骨特异性性酸酶 (BALP),骨质素 (OC),1型公原1型N终端 (P1NP) 和CTx.
- 在基线,赛后和赛后24小时评估了25...OH) D,SII和心脏代谢参数.
主要成果:
- 跑步者比对照者具有更高的25-OH-D和骨周转生物标志物.
- 赛后OC,BALP,P1NP和CTx显著增加,在24小时内恢复到基线 (P1NP除外).
- 骨生物标志物与彼此以及与维生素D相关;OC和25(OH) D显示与血压和BMI的反相关. SII与跑步者的骨生物标志物没有相关性.
结论:
- 半程马拉松训练和急性跑步会提高骨循环生物标志物.
- 需要进一步的研究来确定这些变化对骨健康的长期影响.
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