在癌症患者中脑血管和外周血管并发症
Julien Rousseau1,2,3, Patrick Y Wen4,5
1Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. julien_rousseau@dfci.harvard.edu.
Current neurology and neuroscience reports
|July 1, 2025
概括
癌症患者因癌症本身和免疫疗法等治疗而面临更高的中风和血栓风险. 早期检测和多学科护理对于管理这些血管并发症至关重要.
科学领域:
- 在瘤学瘤学.
- 神经学 神经学
- 血管医学 血管医学
背景情况:
- 癌症显著增加了脑血管疾病的风险.
- 血管并发症对癌症患者的发病率和死亡率有很大影响.
研究的目的:
- 审查癌症患者中风和血栓形成的流行病学,机制和结果.
- 综合关于与癌症疗法相关的大脑血管风险的证据.
- 强调在瘤学中管理血管疾病的重要性.
主要方法:
- 关于癌症和脑血管疾病的现有证据的文献综述.
- 综合关于缺血性中风,脑静脉鼻血栓 (CVST),静脉血栓栓塞 (VTE) 和内出血 (ICH) 的数据.
- 对癌症治疗对血管风险的影响分析.
主要成果:
- 癌症患者通过hypercoagulability和瘤栓塞等机制增加缺血性中风的风险.
- 静脉血栓栓塞 (VTE) 在脑瘤患者中很常见,直接口服抗凝剂显示出有前途.
- 癌症疗法 (例如,免疫检查点抑制剂,激素疗法,辐射) 会增加脑血管疾病的风险.
结论:
- 癌症中的血管并发症是未被认可的,但对患者结果的关键决定因素.
- 多学科方法和个性化风险评估对于改善护理至关重要.
- 需要有针对性的研究来解决癌症和血管疾病之间的复杂相互作用.
相关概念视频
Peripheral Artery Disease V: Postoperative Nursing Management
28
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
28
Venous Thrombosis IV: Nursing Management
27
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
27
Peripheral Artery Disease IV: Nursing Management
47
The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
47
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
38
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
38
Arteries of the Head and Neck
1.8K
The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
1.8K
Venous Thrombosis III: Interprofessional Care
27
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
27


