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Updated: Sep 17, 2025

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人类葡萄糖皮质体受体变体rs6190增加血液中的胆固醇,并促进动脉样硬化

Hima Bindu Durumutla1,2, April Haller3, Greta Noble1

  • 1Molecular Cardiovascular Biology, Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

The Journal of clinical investigation
|July 1, 2025
PubMed
概括

葡萄糖皮质体受体 (GR) 的遗传变异增加胆固醇和动脉样硬化风险,特别是在女性中. 这种SNP增强了GR活性,影响胆固醇代谢和心血管疾病风险因素.

关键词:
动脉样硬化是一种动脉样硬化.胆固醇 胆固醇 胆固醇内分泌学 在内分泌学.表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.遗传学 是一个遗传学.代谢过程中的代谢.

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