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研究伦理中的脆弱性:对政策指导方针和文件的系统审查
Asia Grigis1,2, Giorgia Beretta3, Pascal Borry4
1University of Milan, Milan, Italy.
PloS one
|July 1, 2025
概括
了解研究伦理方面的脆弱性是公平参与的关键. 政策文件往往定义的是弱势群体,而不是弱势本身,影响了知情同意过程.
科学领域:
- 生物伦理学生物伦理学
- 研究伦理学研究伦理学
- 人类受试者研究研究
背景情况:
- 历史研究强调了公平参与研究的需要.
- 在研究中保护弱势个体至关重要,但定义和操作性仍在争论中.
- 在研究中对弱势群体的定义,识别和政策实施方面仍存在分歧.
研究的目的:
- 在PRISMA-Ethics的指导下,系统地审查有关研究伦理的政策文件.
- 为如何在研究伦理学中概念化和操作化脆弱性提供全面的概述.
- 调查与研究中的脆弱性相关的含义,定义,规范性理由,范围和规定.
主要方法:
- 从多个数据库和灰色文献中对政策文件进行系统审查.
- 包括英语国家和国际人类研究伦理政策文件,解决脆弱性.
- 数据分析遵循QUAGOL方法,没有自动化工具.
主要成果:
- 审查中包括了79份政策文件.
- 经常出现的模式表明,人们倾向于定义脆弱群体,而不是脆弱本身.
- 脆弱性往往是根据知情同意程序来定义的.
结论:
- 清楚地了解脆弱性及其理由对于公平和道德的研究参与至关重要.
- 政策文件往往侧重于确定特定的弱势群体,而不是普遍的定义.
- 需要进一步澄清,以确保对所有研究参与者的一致和尊重措施.
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