通过开放的生长板块固的内钉是否会造成伤害? 一个范围审查审查
EFORT open reviews
|July 1, 2025
概括
骨髓内锁钉 (IMN) 可能导致儿童膝关节损伤的有限生长障碍. 然而,超过体质违规门可能会导致不良结果,需要进一步研究安全指南.
科学领域:
- 整形外科手术 整形外科手术
- 儿科整形外科 儿科整形外科
- 生物医学工程 生物医学工程
背景情况:
- 在骨不成熟的患者中,生长板损伤需要谨慎管理,以防止长期变形.
- 骨髓内锁钉 (IMN) 用于骨折固定,但它们对开放生长板的影响,特别是膝盖,尚未完全理解.
研究的目的:
- 绘制有关生长板损伤影响的现有文献,在儿科患者的膝盖使用IMNs.
- 评估临床和实验结果,重点关注诸如生长停止和形等并发症.
主要方法:
- 根据PRISMA扩展指南进行了范围审查.
- 在主要数据库 (PubMed,Embase,Cochrane,Web of Science,Scopus) 进行相关临床和动物研究的搜索.
- 纳入标准侧重于在膝关节接受IMN治疗的儿童患者,这些儿童患有开放生长板,以及骨损伤的动物模型.
主要成果:
- 包括10项研究 (6项临床,3项动物,3项综述),涉及89名儿科患者.
- 在临床病例中没有报告增长停止;动物研究表明,<7%的体质损伤通常是安全的,但更高的百分比导致增长抑制.
- 移除植入物显示出混合的结果,在某些情况下,早期的骨桥形成.
结论:
- 有限的IMNs的身体损伤可能不会导致显著的生长障碍,但超过值可能会导致不良影响.
- 目前的证据不足以提供有关IMN在膝关节骨不成熟患者使用的建议.
- 进一步的研究是必要的,以确定长期的结果,并建立安全的体器仪表指南.
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