诊断和管理退行性宫骨髓病变
Charles-Antoine Mechas1, Mohamed Sarraj, Melvin Helgeson
1From the Department of Orthopaedic Surgery, Division of Spine Surgery, Mayo Clinic, Rochester, MN.
概括
退行性宫肌病 (DCM) 治疗已经发展,现在建议对客观症状进行早期手术. 手术减压旨在阻止进展并改善功能,但仔细的技术和患者选择至关重要.
科学领域:
- 神经外科 神经外科
- 整形外科手术 整形外科手术
- 脊髓医学 脊髓医学
背景情况:
- 退行性宫髓病 (DCM) 呈现出各种进展和症状,如步态障碍和运动缺陷.
- 从历史上看,保守的管理是早期DCM的偏好,但目前的证据支持早期手术干预.
- DCM包括诸如椎脊髓炎和后纵带带骨化等疾病.
研究的目的:
- 审查退行性宫髓病症 (DCM) 治疗方面的进展.
- 讨论DCM的自然史,诊断标准和手术指示.
- 概述在DCM管理中使用的各种手术方法和辅助方法.
主要方法:
- 关于退行性宫肌病 (DCM) 治疗的当前文献的综述.
- 对外科手术技术的分析,包括前部,后部和组合方法.
- 评估与DCM手术相关的结果和并发症.
主要成果:
- 具有脊髓压缩成像确认的客观骨髓病症症状是手术的指示.
- 手术选择包括前椎间盘切除和融合 (ACDF),前椎间盘切除和融合 (ACCF),宫椎间盘关节整形,层状整形和带有融合的层状切除.
- 手术成功的定义是脊髓减压,停止症状进展和潜在的功能改善.
- 像Riluzole这样的辅助疗法显示出有前途.
- 术后并发症可能是严重的,强调了手术技术和患者选择的重要性.
结论:
- 对于具有客观症状的退行性宫骨髓病 (DCM) 患者,越来越多地推早期手术干预.
- 有一系列的手术技术可用,患者选择和细致的技术是成功结果的关键.
- 虽然手术可以阻止进展并改善功能,但对潜在的术后并发症保持警是必不可少的.
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