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Updated: Sep 17, 2025

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

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Published on: September 20, 2016

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获得的SMARCA4变化:在肺腺癌中癌症进展的不常见因素

Andréanne Gagné1, Joao Victor M Alessi2, Biagio Ricciuti2

  • 1Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston MA 02115, USA.

Lung cancer (Amsterdam, Netherlands)
|July 1, 2025
PubMed
概括

获得的SMARCA4突变在非小细胞肺癌中罕见,但在治疗期间可能出现,可能导致瘤进展. 这些遗传变化可能与瘤突变负担增加和瘤特征改变有关.

关键词:
获得的突变 获得的突变功能丧失 功能丧失非小细胞肺癌的肺癌.这就是SMARCA4的标志.

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