蛋白质隔离剂补充剂和尿路结石风险
Daniel G Wong1, Bradley McNeely1, Joel Vetter1
1Division of Urological Surgery, Washington University in St. Louis, St. Louis MO.
Urology
|July 1, 2025
概括
与乳清蛋白相比,豆和大豆蛋白补充剂可能会降低尿路,增加pH值. 然而,豆蛋白也增加了尿氧酸盐,影响了结石风险因素.
科学领域:
- 营养生物化学 营养生物化学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 代谢研究的研究.
背景情况:
- 高蛋白饮食是健康和健身的热门饮食.
- 了解不同蛋白质补充剂对尿路的影响对于预防结石至关重要.
- 乳清,豆,大豆和大米蛋白质分离物是常见的食补充剂.
研究的目的:
- 为了比较乳清,豆类,大豆和大米蛋白质分离物对尿路结石风险因素的影响.
- 为了描述消费特定蛋白质来源的石化性.
主要方法:
- 这是一项涉及9名健康志愿者的交叉研究.
- 参与者每天食用5天的饮食计划,每天三次20克的蛋白质摇,蛋白质分离物 (乳清,豆类,大豆,大米) 不同.
- 每阶段进行两次24小时尿液采集,以分析尿中代谢物.
主要成果:
- 与乳清蛋白相比,豆和大豆蛋白的消费导致尿显著降低,尿液pH值更高.
- 尿液中氧酸盐与豆蛋白相比,与乳清蛋白相比,在豆蛋白中显著更高.
- 蛋白质类型之间没有观察到酸盐分泌或氧酸盐超和的显著差异.
结论:
- 不同的蛋白质分离物对尿路代谢产物有明显的短期影响.
- 氨基酸形状和其他粉末成分 (,阳离子) 的变化可能有助于这些差异.
- 需要进一步的研究才能充分了解尿路结石形成的长期影响.
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