一个有前途的可食用的基于环氧的金属有机框架:从制备,表征到应用在食品中的活性成分加载中
Jiaxuan Song1, Xiang Liu2, Xu Yang2
1College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
International journal of biological macromolecules
|July 1, 2025
概括
基于环氧的金属有机框架 (CD-MOF) 为封装活性成分提供了一个天然的,可食用的解决方案. 这些可生物降解材料增强了稳定性,有针对性的输送和在食品系统中控制的释放.
科学领域:
- 食品科学与技术 食品科学与技术
- 材料科学 材料科学 材料科学
- 纳米技术 纳米技术
背景情况:
- 对食品安全和健康促进的日益增长的需求需要新的封装材料.
- 基于环氧的金属有机框架 (CD-MOF) 成为具有可取性质的有希望的可食MOF.
- CD-MOF结合了MOF的好处 (多孔性,功能部位) 与环极素 (无毒性,生物相容性).
研究的目的:
- 审查CD-MOF的结构,合成和特性方面的最新进展.
- 总结CD-MOF在加载,保护和控制食品中活性成分的释放中的应用.
- 探索食品工业中CD-MOF发展的未来前景.
主要方法:
- 文献综述侧重于CD-MOF的最近研究 (过去五年).
- 对CD-MOF的结构,合成和物理化学特性进行分析.
- 评估CD-MOF在食品矩阵中的应用,以提供活性成分.
主要成果:
- CD-MOFs表现出极好的内部/外部水友性,吸附,分离和生物相容性.
- 将活性成分加载到CD-MOF中可以提高其稳定性,并实现有针对性的,可控的释放.
- 最近的研究强调了在食品,生物医学和环境保护领域的多样化应用.
结论:
- CD-MOF代表了食品行业可食用封装材料的重大进步.
- 它们的独特特性促进了活性食品成分的增强稳定性和受控释放.
- 新型CD-MOF复合物的进一步开发对未来的应用有很大的前景.
相关概念视频
Bioavailability Enhancement: Drug Stability Enhancement and GI Retention
Improving a drug's stability in the gastrointestinal (GI) tract is paramount for enhancing its bioavailability and therapeutic effectiveness. Various strategies are employed to protect the drug from the harsh gastric milieu and to ensure its release and absorption at the desired site within the GI tract.Polymer coatings are one such method used to shield drugs from the stomach's acidic environment. By preventing premature drug release, these coatings improve the bioavailability of unstable...
Site-Targeted Drug Delivery Systems: Polymeric Carriers
Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...


