肥胖对放射性变化的影响在患有扩散性异常性骨超静止症的患者中
David Kiefer1, Michail Godolias2, Philipp Sewerin3
1D. Kiefer, MD, Ruhr-Universität Bochum, Rheumazentrum Ruhrgebiet, Herne, Germany.
The Journal of rheumatology
|July 1, 2025
概括
有三分之一的代谢综合征 (MetS) 患者患有扩散性异常性骨架强症 (DISH). 在MetS患者中,较高的肥胖类与DISH特征的脊柱变化有关,而不是退行性变化.
科学领域:
- 类风湿病学 类风湿病学
- 整形外科 整形外科 整形外科
- 放射学 放射学是一门学科.
背景情况:
- 扩散性异常性骨高静止症 (DISH) 涉及化和骨化,主要发生在轴骨中.
- DISH经常与代谢综合征 (MetS) 组成部分,如肥胖,糖尿病和高血压有关.
研究的目的:
- 为了确定DISH在MetS患者中的患病率.
- 评估肥胖对脊柱放射变化的影响,区分DISH和退行性变化.
主要方法:
- 124名MetS患者被分为肥胖类 (WHO标准) 和按DISH状态 (Resnick标准) 分类.
- 放射图分析了退行性脊髓细胞 (d-脊髓细胞) 和与DISH相关的块状脊髓细胞 (Drc-脊髓细胞).
- 在统计学上分析了肥胖类别和脊髓细胞类型之间的关联.
主要成果:
- 在124名MetS患者中,DISH在33.9%的患者中被发现.
- 更高的肥胖类 (II和III) 与更多的Drc-spondylophytes有显著的相关性.
- 肥胖与d-脊髓细胞无关,而DISH患者的d-脊髓细胞比非DISH患者少.
结论:
- 大约三分之一的MetS患者表现出DISH.
- 在MetS患者中,严重的肥胖 (II和III类) 与与DISH相关的脊柱变化有显著的关联,与退行性变化不同.
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