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突变的p53诱导SH3BGRL的表达,以促进细胞吞

Lobsang Dolma1,2, Mary I Patterson1, Antonia Banyard2

  • 1Biosciences, Durham University, Durham, UK.

Cell death discovery
|July 1, 2025
PubMed
概括

突变的p53表达驱使癌细胞吞邻居,形成细胞内细胞结构. 这一过程需要SH3BGRL,增强化学抵抗性和独立于 anchorage的生长,有助于突变p53的功能获取.

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