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Updated: Aug 11, 2026

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一种生物模拟的多组分子单位疫苗,通过对等级的水凝进行比值加载

Fanfan Du1,2, Simseok A Yuk2, Yuan Qian2

  • 1Department of Biomedical Engineering, NanoSTAR Institute, University of Virginia School of Medicine, Charlottesville, VA, USA.

Nature communications
|July 1, 2025
PubMed
概括

这项研究引入了子单位疫苗的新型水凝储存库,使抗原和多种辅助剂的联合递送成为可能. 这些纳米凝疫苗显著增强免疫反应,为未来的疫苗开发提供了一个有希望的平台.

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Vaccine Production01:23

Vaccine Production

Vaccine production involves a sequence of upstream and downstream processes to generate a safe and effective immunological product. It begins with cultivating microorganisms, such as viruses or bacteria, to obtain antigenic material. For viral vaccines, mammalian host cells are grown in bioreactors and subsequently infected with the target virus. The virus replicates within the host cells, which are lysed to release viral particles. This lysate is then clarified through filtration or...