从1967年到2023年,全球估计的与疫苗相关的麻醉症
Yi Deun Jeong1,2, Hyesu Jo3,4, Yesol Yim2,5
1Department of Medicine, Kyung Hee University College of Medicine, Seoul, South Korea.
Scientific reports
|July 1, 2025
概括
流感疫苗显示了麻醉症风险的最强烈信号,特别是在青少年和男性中. 尽管有众多报告,但COVID-19 mRNA疫苗没有显示麻醉症信号.
科学领域:
- 药监和流行病学 药监和流行病学
- 疫苗安全研究 疫苗安全研究
- 神经学 神经学
背景情况:
- 关于接种疫苗后麻醉症风险的全球数据有限.
- 了解与疫苗相关的麻醉症对于全球疫苗接种策略至关重要.
研究的目的:
- 为了评估与疫苗相关的麻醉症的全球估计.
- 为了确定与麻醉相关的特定疫苗.
- 为了制定更安全的疫苗接种方案.
主要方法:
- 使用了国际药监数据 (1967-2023年).
- 分析了140个国家的16种疫苗的全球报告数量,ROR和IC.
- 研究了特定于年龄和性别的信号和发病时间.
主要成果:
- 自2009年以来,确定了2,183起与疫苗相关的麻醉症报告.
- 对流感 (ROR 156.53),乳头瘤病毒和脑炎疫苗检测到的最高信号.
- 麻醉症信号在12-17岁的男性中突出,平均发病时间为115天.
- COVID-19 mRNA疫苗没有显示对麻醉症的信号检测.
结论:
- 流感疫苗表现出对麻醉症的最强信号,其次是乳头瘤病毒和脑炎疫苗.
- 与疫苗相关的麻醉症主要在青少年男性中观察到.
- 这些发现并不能推断因果关系,但突出了麻醉症的特定疫苗风险.
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