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Updated: Sep 17, 2025

Profiling Sensitivity to Targeted Therapies in EGFR-Mutant NSCLC Patient-Derived Organoids
08:52

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奥西默蒂尼布加上化疗与奥西默蒂尼布,用于患有同时发生EGFR和TP53突变的晚期NSCLC患者:前性队列研究

Jixian Li1, Xiang Zhan1, Mengqing Shao2

  • 1Shandong Provincial Hospital, Shandong University, Jinan City, 250021, Shandong Province, China.

Scientific reports
|July 1, 2025
PubMed
概括

将化疗添加到奥西默蒂尼布可能会改善EGFR和TP53共同突变的非小细胞肺癌 (NSCLC) 患者的结果. 这种组合疗法显示出更好的反应率和无进展生存率的趋势,特别是在L858R突变患者中.

关键词:
化疗 化疗是一种化学疗法.欧洲农业基金会 (EGFR) 是一个基金.在NSCLCLC中,我们可以看到NSCLCLC.奥西默蒂尼布 (Osimertinib) 是一种药物.这就是TP53的特点.

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