相关实验视频

Updated: May 12, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
11:15

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Published on: September 20, 2016

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一个有针对性的下一代测序小组,用于确定固体瘤中临床相关的突变概况

Kakoli Das1, Mandy Li Ian Tay2, Elena Yaqing Yong2

  • 1Department of Pathology, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, 308433, Singapore. kaks23@yahoo.com.

Scientific reports
|July 2, 2025
PubMed
概括

一个新的癌症基因瘤测试提供了高准确性和速度. 这种定向的下一代测序试验显著减少了基因组分析的周转时间,改善了及时的患者护理.

关键词:
癌症 癌症 癌症 癌症基因组学就是基因组学.没有NGS,没有NGS.在Oncopanel上使用.身体突变的体质突变有针对性的测序.

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Tumor Progression02:07

Tumor Progression

Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
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Cancer-Critical Genes II: Tumor Suppressor Genes

Genes usually encode proteins necessary for the proper functioning of a healthy cell. Mutations can often cause changes to the gene expression pattern, thereby altering the phenotype.
When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
Such genes that act...