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Updated: Sep 17, 2025

Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors
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Genetically-encoded Molecular Probes to Study G Protein-coupled Receptors

Published on: September 13, 2013

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遗传密码扩展,使活细胞中的G蛋白结合受体能够进行特定站点的翻译后片标记

Jordan M Mattheisen1,2, Thomas Huber1, Thomas P Sakmar3

  • 1Laboratory of Chemical Biology and Signal Transduction, The Rockefeller University, New York, NY, USA.

Methods in molecular biology (Clifton, N.J.)
|July 2, 2025
PubMed
概括

这项研究引入了一种新的后翻译方法,用于使用非正规氨基酸 (ncAAs) 和生物对角化学来标记表位蛋白质. 这种技术使活细胞中的蛋白质能够精确标记,为蛋白质检测和净化提供了新的可能性.

关键词:
抑制珀色密码子的抑制.生物对等反应的生物对等反应上层层是什么意思 上层是什么意思G蛋白结合受体的受体是G蛋白结合受体的受体.遗传密码扩展 遗传密码扩展后翻译 后翻译

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