语境灵活调节视觉皮层中的暗示表示
Alexa D Faulkner1,2, Alvin S Chiu1,2, Armin Sarabi3
1Michigan Neuroscience Institute, University of Michigan, Ann Arbor, MI, USA.
Nature communications
|July 2, 2025
概括
学习识别感官线索可以增强大脑的反应,指导决策. 环境的变化,就像威胁一样,迅速改变这些神经表征,但保留了关键的学习反应.
科学领域:
- 神经科学是一个神经科学.
- 系统神经科学 系统神经科学
- 感官处理 感官处理
背景情况:
- 学习的感官线索增强神经反应,影响注意力和决策.
- 适当的反应需要识别线索和它们周围的背景.
- 对于灵活的行为来说,大脑适应神经表征以适应不断变化的环境的能力至关重要.
研究的目的:
- 研究视觉皮层如何在不同的外部环境下代表学习的线索.
- 检查依赖上下文的提示处理和决策的基础的神经机制.
- 在外部环境快速变化时,确定神经表示的灵活性.
主要方法:
- 在小鼠视觉皮层中利用两光子成像.
- 训练小鼠进行视觉区分任务.
- 通过引入威胁刺激并随后减轻它来操纵外部环境.
主要成果:
- 与奖励相关的刺激引起了增强的反应,包括增加反应大小和招募新神经元.
- 引入威胁刺激导致了一组独特的神经元编码线索,同时保留对奖励线索的增强反应.
- 神经表征在威胁被移除后恢复到最初的状态.
结论:
- 外部环境显著影响感官皮层中学习的视觉线索的表现.
- 神经表现显示出快速而灵活的转变,以应对不断变化的环境环境.
- 大脑根据即时的上下文相关性,如威胁或奖励的存在,动态调整提示处理.
相关概念视频
Vision
55.4K
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
55.4K
Depth Perception and Spatial Vision
956
Depth perception is the ability to perceive objects three-dimensionally. It relies on two types of cues: binocular and monocular. Binocular cues depend on the combination of images from both eyes and how the eyes work together. Since the eyes are in slightly different positions, each eye captures a slightly different image. This disparity between images, known as binocular disparity, helps the brain interpret depth. When the brain compares these images, it determines the distance to an object.
956
Motor and Sensory Areas of the Cortex
4.7K
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex....
4.7K
Color Vision
729
Color perception begins in the retina, the light-sensitive layer at the back of the eye. Two main theories explain how colors are seen: the trichromatic theory and the opponent-process theory. The trichromatic theory, proposed by Thomas Young in 1802 and extended by Hermann von Helmholtz in 1852, suggests that color vision is based on three types of cone receptors in the retina. These cones are sensitive to different but overlapping ranges of wavelengths corresponding to red, blue, and green.
729
Perceptual Constancy
568
Perceptual constancy is the ability to recognize that objects remain consistent and unchanged even when their appearance varies due to changes in sensory input. There are four main types of perceptual constancy: size constancy, shape constancy, color constancy, and brightness constancy.
Size constancy is the recognition that an object remains the same size, even when its image on the retina changes. For instance, a bus is perceived to be large enough to carry people, even if it looks tiny from...
Size constancy is the recognition that an object remains the same size, even when its image on the retina changes. For instance, a bus is perceived to be large enough to carry people, even if it looks tiny from...
568
Visual System
705
Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...
Once through the pupil, the light passes through the lens, a...
705


