控制食品微生物组的代谢稳定性,以实现稳定的本土液体发酵
Yuwei Tan1,2, Yang Zhu2, René H Wijffels2,3
1Laboratory of Brewing Microbiology and Applied Enzymology, Key Laboratory of Industrial Biotechnology of Ministry of Education, Jiangnan University, Wuxi, 214122, Jiangsu, China.
NPJ biofilms and microbiomes
|July 2, 2025
概括
为了实现食品生产的稳定微生物发酵,需要了解微生物组的动态. 本研究确定了影响稳定性的关键因素,并提供了用于加强本土液体发酵控制的实际方法.
科学领域:
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
- 生物技术是生物技术.
背景情况:
- 微生物的代谢稳定性对于稳定,高质量的食品生产至关重要.
- 本土液体发酵依赖于复杂的微生物组,对工艺控制和产品的一致性构成挑战.
- 现有的方法很难将这些复杂的系统引导到可预测的结果.
研究的目的:
- 确定导致复杂发酵过程中代谢不稳定的因素.
- 在实验室环境中探索指导和增强发酵稳定性的策略.
- 为控制和高效的微生物食品生产提供见解.
主要方法:
- 设计了一种三步实验方法来研究微生物的代谢稳定性.
- 分析重点是发酵参数,微生物相互作用 (酵母和乳酸菌),以及代谢网络冗余.
- 实验室规模的发酵设置被用来控制和观察稳定性因素.
主要成果:
- 微生物组的代谢稳定性受到发酵参数,酵母和乳酸菌之间的动态效益分配以及代谢网络冗余的影响.
- 短期稳定性取决于持续的微生物益处分配.
- 长期稳定性与微生物组内适当的功能冗余有关.
结论:
- 通过合理控制初始参数和微生物注射比率,可以实现优化发酵稳定性.
- 通过适当的初始条件来提高发酵稳定性是可行的,这导致了更受控制的微生物食品生产.
- 这项研究为工业应用提供了对微生物组代谢控制的新见解.
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