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骨矿物质密度,腹部脂肪和准脊椎肌肉之间的年龄和性别特异关系

Lei Gao¹, Ying Liu¹, Wei Zhang¹

¹Department of Radiology, Hebei Medical University Third Hospital, No. 139 Ziqiang Road, Qiaoxi District, Shijiazhuang, 050051, Hebei Province, China.

Scientific reports

|July 2, 2025

概括

身体组成因性别和年龄而异. 在50岁以上的女性中,骨密度和腹部脂肪与准脊椎肌肉退化相关,这表明肌肉健康的潜在预测因素.

科学领域:

内分泌学在内分泌学.
老年学是一门学科.
放射学放射学是一门学科.

背景情况:

骨,肌肉和脂肪组织是具有复杂相互作用的关键内分泌器官.
了解身体成分的性别和年龄相关变化对健康至关重要.
骨矿物质密度 (BMD),腹部脂肪和准脊椎肌肉之间的相互作用需要进一步研究.

研究的目的:

分析身体组成的性别和年龄特异性差异.
研究BMD,腹部脂肪和副脊椎肌肉之间的相关性.
为了探索潜在的预测器的准脊椎肌肉退化.

主要方法:

定量计算断层扫描 (QCT) 用于评估376名受试者的骨质量,内脏脂肪区域 (VFA),皮下脂肪区域 (SFA),准脊椎肌肉截面区域 (CSA) 和肌肉间脂肪组织 (IMAT).
计算了肌肉的脂肪透率 (FF).
使用标准化体质成分指标 (使用BMI) 和部分相关性分析.

主要成果:

与男性相比,女性的VFA/BMI和椎肌肉CSA/BMI较低,但SFA/BMI较高.
肌肉FF在50岁以下的女性中更高.
在50岁以上的女性中,BMD与MF-ES FF有负相关性,而VFA和SFA与MF-ES和psoas FF有正相关性.
衰老导致MF-ES缩和IMAT增加,而psoas缩减少了CSA.

结论:

性别和年龄显著影响身体组成,包括脂肪分布和肌肉特征.
骨髓质量和腹部脂肪与中年和老年妇女的准脊椎肌肉缩有关.
这些发现突出了特定的人口结构中准脊椎肌肉退化潜在的预测标志物.

关键词:

骨矿物质密度骨矿物质密度计算机断层扫描 (CT) 是一种计算机断层扫描.脂肪的透;腹部脂肪的透;腹部脂肪的透.副脊柱肌肉副脊柱肌肉副脊柱肌肉副脊柱肌肉

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