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Updated: Sep 17, 2025

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基因组 lysine 甲基转移酶 MLL3 和 MLL4 直接基因表达以有效地产生血小板

Guozhen Gao1, Josimar Dornelas Moreira1, Prosun Das2

  • 1Department of Epigenetics and Molecular Carcinogenesis, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Nature communications
|July 2, 2025
PubMed
概括

染色体调节器MLL3和MLL4对于血小板的产生至关重要. 它们的缺乏会损害巨核细胞的成熟,导致巨血小细胞减少和血小板的快速清除.

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