用大型语言模型提取的精神疾病知识图模块的近距离关系的研究
Zihan Zhou1,2, Ziyi Zeng1,2, Wenhao Jiang3
1School of Automation, Nanjing University of Information Science and Technology, Nanjing, 210044, China.
Scientific reports
|July 2, 2025
概括
这项研究使用知识图来分析精神疾病,发现更近的疾病和症状网络距离预测了类似的临床特征和共同发生,有助于诊断和治疗.
科学领域:
- 医疗信息学 医疗信息学
- 精神病学是一个精神病学.
- 计算语言学 计算语言学
背景情况:
- 越来越多的精神疾病发病率给全球健康带来了挑战.
- 需要先进的知识系统和用于诊断和治疗的分析方法.
研究的目的:
- 开发一个本体学模型和实体类型,用于心理疾病.
- 为分析疾病,症状和药物关系构建知识图.
- 识别预测疾病相似性,症状并发和诊断价值的模式.
主要方法:
- 使用BERT和LoRA调整的大型语言模型 (LLM) 进行命名实体识别.
- 构建了一个知识图,包括9668个三倍数.
- 分析疾病,症状和药物模块之间的网络距离.
- 对症状与疾病关系的近距离得分进行比较.
主要成果:
- 疾病之间的更密切的网络距离与类似的临床表现,治疗和心理机制相关.
- 症状之间较近的网络距离表明共发生的可能性更高.
- 在初级诊断关系中,症状-疾病对显示出更强的关联和更高的参考值.
结论:
- 知识图显示疾病,并发症状和治疗策略之间的潜在联系.
- 这些发现为诊断和治疗精神疾病提供了新的视角.
- 为未来的心理健康研究和临床实践提供了宝贵的见解.
更多相关视频
05:47Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
592
03:14Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
Published on: December 6, 2024
692
相关概念视频
Classification of Illness
8.0K
The meaning of illness is individualized to each person who experiences an alteration in health. In contrast, disease is a medical term indicating a pathological change in the structure and function of the body or mind. It is a condition that has specific symptoms and boundaries.
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
An illness is a response to a disease in which the person's level of functioning is changed compared with a previous level. The general classification of illness includes acute and chronic.
Acute illness is severe...
8.0K
Human Genetics
738
Human genetics provides a profound framework for understanding the interplay between genetic predispositions and human psychology. At the heart of this discipline lies the study of how genes influence physical traits, behaviors, and susceptibility to diseases. Each person carries a unique genetic code that subtly or significantly shapes their psychological and behavioral landscape.
The complex relationship between genetics and psychology is observable through common biological components such...
The complex relationship between genetics and psychology is observable through common biological components such...
738
Models of Health Promotion and Illness Prevention II
1.7K
The person's health status fluctuates continually, varying from being in good health to becoming ill and returning to being healthy. To understand the concept of illness prevention, there are two models. First, the health-illness continuum model is a graphic representation of an individual's wellness. It states that a person is considered healthy in the absence of physical disease and the presence of good emotional health.
The agent-host-environment model states that disease results...
The agent-host-environment model states that disease results...
1.7K
Causality in Epidemiology
899
Causality or causation is a fundamental concept in epidemiology, vital for understanding the relationships between various factors and health outcomes. Despite its importance, there's no single, universally accepted definition of causality within the discipline. Drawing from a systematic review, causality in epidemiology encompasses several definitions, including production, necessary and sufficient, sufficient-component, counterfactual, and probabilistic models. Each has its strengths and...
899
Models of Health Promotion and Illness Prevention I
2.2K
A model is a theoretical way to understand a concept or an idea. Models can overcome barriers to health regardless of diverse economic and cultural backgrounds. In addition, models make the task easier by providing different ways to approach complex issues. There are two major health promotion models: the health belief model and the health promotion model.
The health belief model (HBM) attempts to predict health-related behavior in specific belief patterns. According to the HBM, a person's...
The health belief model (HBM) attempts to predict health-related behavior in specific belief patterns. According to the HBM, a person's...
2.2K
Concepts of Health and Illness
15.6K
Health is a condition of the body, mind, and spirit where an individual remains free from illness. Similarly, wellness is an active state, including living a lifestyle that promotes physical, mental, and emotional health. Physical health is critical for the overall well-being and can be affected by lifestyle, activity level, diet, and behavior. The highest attainable standard of health is a fundamental and universal human right. Consider Lisa, a fifteen-year-old born with congenital...
15.6K
