可解释的纵向玻璃眼视野估计深度学习系统从 fundus 图像和临床叙述
Xiaoling Huang1, Xiangyin Kong2, Yan Yan1
1Zhejiang University, Eye Center of Second Affiliated Hospital, School of Medicine, Zhejiang Provincial Key Laboratory of Ophthalmology. Zhejiang Provincial Clinical Research Center for Eye Diseases. Zhejiang Provincial Engineering Institute on Eye Diseases, Hangzhou, China.
NPJ digital medicine
|July 2, 2025
概括
这项研究引入了一个深度学习系统,以从眼睛图像和临床笔记中预测青光眼的视力丧失. 该工具有助于有效的长期患者监测和评估.
科学领域:
- 眼科医生 眼科 眼科
- 医疗成像医学成像
- 人工智能的人工智能
背景情况:
- 玻璃眼是全球不可逆转的失明的主要原因.
- 视野 (VF) 测试对于对青光眼的评估至关重要,但耗时且需要患者的合作.
- 彩色底部照片 (CFP) 为监测疾病进展提供了一个可访问的替代方案.
研究的目的:
- 开发一个多模式纵向估计深度学习 (MLEDL) 系统.
- 使用CFP和临床文本预测当前和未来视野 (VF) 状态.
- 为了提高绿眼病患者监测的效率和可靠性.
主要方法:
- 开发了一个MLEDL系统,利用横截面和纵向数据集.
- 在广泛的患者记录上训练并验证了模型 (1598个横截面,3278个纵向,446个外部测试记录).
- 采用VF分级方法进行临床验证,并生成热图以可视化与疾病相关的损害.
主要成果:
- 该MLEDL系统展示了准确的VF预测能力.
- 整个模型的点向平均绝对误差在3.098到4.131dB之间.
- 热图有效地说明了底部损伤和视力丧失之间的相关性,证实了临床可靠性.
结论:
- 该MLEDL系统有效地预测CFP和临床叙述的视觉场.
- 这项技术为长期格劳科马评估提供了一个潜在的工具,并提高了临床效率.
- 促进对随着时间的推移而发生的青光眼的进展进行非侵入性,可靠的监测.
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